by Alicja Brożek, Christina V. Theodoris • 1 month ago
A new AI model developed by researchers at the Gladstone Institute analyzes chromatin accessibility data from over 200 cell types to predict gene expression. This model aims to understand how different chromatin landscapes influence transcriptional states and regulatory sequences, essential for diverse cellular functions. The study highlights the significance of epigenetic modifications in gene regulation, depending on the cell's context, such as developmental stage or disease state.