Generative AI (GenAI) is transforming supply chain and operations, offering organizations significant cost savings by optimizing processes. While many have focused on administrative tasks, leaders are encouraged to apply GenAI to critical areas like Cost of Goods Sold and Operating Expenses for greater value. Challenges include managing unstructured data and integrating with legacy systems. A strategic, iterative approach is recommended, emphasizing quick deployment and collaboration with experienced partners to maximize GenAI benefits.