The concept of the self-driving enterprise, championed by Kiran Yelamaneni, envisions organizations that autonomously manage operations using AI, machine learning, and automation. These enterprises promise enhanced efficiency, data-driven decision-making, and reduced human intervention. However, challenges like incomplete data, ethical AI concerns, and governance issues remain. To realize this vision, businesses must invest in technology, develop data strategies, and ensure responsible AI integration while fostering innovation and adapting to market changes.